Just recently I published a tutorial on how to get good scans with Epson´s native scanning software "Epson Scan". In addition to this tutorial I recorded a short screencast to supplement this tutorial and elaborate some further details. Unfortunately I only have German copy of Epson scan so please bear with me that I used this version for the screencast. In the mentioned tutorial you can find screencasts from the English version of Epson Scan in order to follow along the tutorial.
Hope you enjoy the video...